Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Novel Benzofuran Derivatives as Potent LSD1 Inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Novel Indole Derivatives as LSD1 Inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Dual EZH2 & LSD1 Inhibitor (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of 2‑Aryl-4-aminoquinazolin-Based LSD1 Inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Novel 1H‑Pyrrolo[2,3‑c]pyridin Derivatives Based Lysine Specific Demethylase 1 Inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Dual LSD1 and HDAC Inhibitor (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Novel acridine-based LSD1 inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Dual LSD1 & HDAC Inhibitor (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of Novel 5‑Cyano-3-phenylindole-Based LSD1/HDAC Dual Inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software

Journal: Journal of Enzyme Inhibition and Medicinal Chemistry

Article Title: Palladium-catalysed synthesis of small-molecule epigenetic inhibitors as anticancer therapeutics

doi: 10.1080/14756366.2026.2621477

Figure Lengend Snippet: Design Strategy & Synthetic Route of CC-90011 (328): A Lysine Specific Demethylase 1 Inhibitors (the figure was drawn by the authors using chemdraw software).

Article Snippet: Duan et al. designed 5-cyano-3-phenylindole-based LSD1/HDAC dual inhibitors for colorectal cancer, inspired by the Novartis LSD1 inhibitor ( 350 ).

Techniques: Software